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The most common side effects of RYBELSUS may include: The most common side effects of RYBELSUS may include: Nausea Vomiting Diarrhea Stomach (abdominal) pain Decreased appetite Constipation Nausea Diarrhea Vomiting Stomach (abdominal) pain Decreased appetite Constipation Nausea Vomiting Diarrhea Stomach (abdominal) pain Decreased appetite Constipation Nausea Diarrhea Vomiting Stomach (abdominal) pain Decreased appetite Constipation Nausea Diarrhea Vomiting Stomach (abdominal) pain Decreased appetite Constipation Nausea, vomiting, and diarrhea are most common when first starting RYBELSUS and when your dose increases

Exercise and injection timing Avoid injecting immediately before or after intense exercise

In the sensitivity analyses, the primary outcome analysis was repeated for the PP sample, defined as participants who followed the study protocol with full adherence, attending all study visits with no substantial interruptions in treatment as monitored from the drug dose diary

See symptoms of serious allergic reaction in What are the possible side effects of RYBELSUS ? What is RYBELSUS