10.1038/s12276-017-0013-x 28 DringenR.ArendC
They can help manage side effects and adjust your treatment if necessary
News provided by Ro Apr 09, 2026, 07:15 ET Foundayo gives patients a new once daily pill option and expands Ro's comprehensive weight loss formulary NEW YORK, April 9, 2026 /PRNewswire/ -- Ro, the leading direct-to-patient healthcare company, today announced eligible patients can now access Foundayo (orforglipron) Eli Lilly Company's newest oral GLP-1 innovation on the Ro platform, adding to Ro's already comprehensive formulary of FDA-approved GLP-1s

Semaglutide is often chosen first if cost is a major barrier, if insurance covers it more reliably, or if someone is nervous about potentially stronger gastrointestinal side effects, and it has a long track record in both diabetes and chronic weight management, so clinicians may start there for a conservative yet effective approach, especially for modest weight loss goals, then consider switching to tirzepatide later if results plateau, side effects remain manageable, and coverage improves, and some practices even map out this stepwise plan during the very first visit