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As of now, GLP-1-related triple agonists are primarily still in the development stage and have not been widely approved for use

Additional Monotherapy Study A multinational, randomized, double-blind, placebo-controlled study was also conducted to assess the safety and tolerability of Januvia in 91 patients with type 2 diabetes and chronic renal insufficiency (creatinine clearance less than 50 mL/min)

Compounded medications are custom-prepared by a licensed compounding pharmacy using active pharmaceutical ingredients sourced from FDA-registered facilities, but the finished compounded product itself doesn't go through the FDA's new drug approval process for safety, effectiveness, and manufacturing quality the way brand-name medications like Ozempic or Wegovy do