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FIGURE 9 Summary and conclusions: Glutathione and early (premature) inflammaging Chronic inflammatory diseases especially those compromising the lower respiratory system (chronic obstructive pulmonary disease, lower respiratory infections, cystic fibrosis, idiopathic pulmonary fibrosis, acute respiratory distress syndrome), diseases compromising the cardiovascular system (atherosclerosis, ischemic heart disease, stroke, and others), many other systemic inflammatory diseases like diabetes (274, 275)

Patients who are already sleeping well, training consistently, and managing weight typically see less dramatic early changes but better long-term composition results

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Qiao L, Men L, Yu S et al (2022) Hepatic deficiency of selenoprotein S exacerbates hepatic steatosis and insulin resistance