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Therefore, in the present study, we used a well-known neurotoxicity cell culture model (human neuronal SH-SY5Y cells) [10] in order to elucidate the potential toxicity (synergistic or not) of caffeine, taurine, and guarana, three components that are commonly present in EDs at high concentrations

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Nanoparticles delivery systems have now emerged as a powerful strategy for facilitating the passage of siRNA over the bloodbrain barrier for AD therapy (97, 98)

Brain 2018;141:1917-33