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The severity of these reactions led to an 18% discontinuation rate in the clinical trial, indicating that nearly one in five patients cannot tolerate the treatment protocol
: Off Label Tourette Syndrome Tics Used to manage motor and phonic tics associated with Tourette syndrome by decreasing noradrenergic hyperactivity (Zhao et al., 2024)
There has many researches about increasing the production of l-cysteine, such as reduced the degradation of l-cysteine by disrupting the l-cysteine degradation genes [19] or overexpressed the l-cysteine synthetases to increase the l-cysteine concentration [20, 21]
10.1124/pharmrev.120.000096 169 YamauchiM.KitamuraY.NaganoH.KawatsuJ.GotohH
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