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GLP-1 enhances glucose-dependent insulin secretion from pancreatic beta cells, inhibits glucagon release from alpha cells, and slows gastric emptying, thereby aiding in blood glucose regulation

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With Wells Fargo employing about 13,000 people in the Des Moines metro, many of them at the West Des Moines headquarters of its mortgage division, the company's plan to shed $9 billion in mortgage lending "is not good news," said Peter Orazem, an Iowa State University labor economist