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In adults with obesity or overweight who have not achieved adequate results from lifestyle changes (like a reduced-calorie diet and increased physical activity) alone, the American Gastroenterological Association (AGA) recommends adding medication to the lifestyle changes rather than continuing with lifestyle modifications alone

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These findings appear to be a result of disease and not other variables such as age or biological sex, as no significant difference in biological sex distribution within the cohort was found (Students t Test, p = 0.98) (Supplementary Data 1)

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