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While there isnt any comprehensive research about whether B12 can help treat symptoms of a hangover, replenishing your body with the vitamins that a night of drinking may have depleted can be helpful

The vitamin is injected directly into muscle (intramuscular) or under the skin (subcutaneous) and is released gradually into the bloodstream

Theoretical and route-specific risks FDA's 2024 review specifically flagged that no published human exposure data exists for the subcutaneous, transdermal, or intranasal routes that compounding pharmacies have offered

Blood tests can help determine if the current dosage is adequate or if adjustments are needed