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Ovaries are often left intact in women who are not at risk for ovarian cancer because they produce estrogen, which helps protect women from conditions such as heart disease and osteoporosis

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Because in pre-menopausal women a PET-positive ovary may be either an adnexal neoplasm or completely normal, it is important to be aware of the possibility of physiologic mid-cycle FDG uptake and to correlate this finding with the clinical history