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Here, we have taken advantage of the glycolytic shift exhibited by DoxyR CSCs, as we have used several glycolysis inhibitors with the aim to turn their strict metabolic inflexibility, into a lethal phenotype

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(A) Unsupervised multivariant principal component analysis (PCA) resulting in F1 and F2 with a cumulative percent variability of 78.56% Each circle represents a TipDC transcriptome, the open circles are control and the solid black IAV