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The peripheral neuropathy in Fabry disease is described as a small fibre neuropathy, meaning that small, unmyelinated nerve fibres are particularly affected [82]

The explanation for that could be due to the noticeable increase in oxidative stress in the testicular tissue, causing Leydig cell destruction

Finally, the applicant stated that, under the regulation at 419.66(a), CMS makes a pass-through payment for a medical device that meets the requirements in paragraph (b) of that section and that is described by a category of devices established by CMS under the criteria in paragraph (c) of that section, and that, further, according to 419.66(g), the pass-through period begins on the first date on which pass-through payment is made

The final libraries were quantified using a Qubit Fluorometer (Thermo Fisher Scientific) with the Qubit dsDNA HS Assay Kit (Thermo Fisher Scientific)